MS Research 2018: Smoking While On Tysabri


Is smoking really that bad for you? In
this video I’ll be reviewing a recently published research article which
discusses the effects of smoking in MS patients taking Tysabri. Want to know the
answer? Stay tuned because I’m going to share starting right now! Howdy! thanks for learning about MS with
me Aaron Boster. I started this YouTube channel to help my own MS clinic
patients learn between clinic visits and it’s my hope that through these videos, I
can help you learn too. I recently published an article where I reviewed a
research abstract, and I was blown away by the responses! The comments suggested that you guys dig this format and so I want to try it again. In this video I’ll
be discussing another research article this one focused on the effects of
smoking in MS, specifically amongst people taking Tysabri. So let’s get
started. Here you see the abstract to the article entitled “Smoking is associated
with increased disease activity during natalizumab treatment for multiple
sclerosis,” first author Peterson. This was published in the Journal of Multiple
Sclerosis in August of this year. In this study, they examined 355 people with
relapsing MS, and all taking Tysabri. They started to look at the clinical data at
the time Tysabri was initiated and they followed these patients for a period of
two years. They determined the smoking status based on a questionnaire response
that each patient filled out. Now what they found really struck me. Ine pack of
cigarettes smoked per day increased this populations risk of having an
attack by 38%! Now let that sink in for a second.
Tysabri is a highly effective medicine and here we have a group of patients
taking this highly effective medicine. If the patient smoked as compared to if
they didn’t, they literally increase the risk of an attack over the period
studied by 38. They increased it by over 1/3 that is very, very concerning. In 2018
MS is not a curable condition but it’s a treatable condition, and we
want to do anything and everything possible to slow down the disease
activity, including stopping or preventing attacks. Here we’ve learned
about a modifiable risk factor, smoking, and yet again we see strong clinical
data suggesting that if you smoke even if you’re taking a highly effective
medicine you increase the risk of clinical attacks, in this study by 38%.
That is a startling statistic. So when I talk about being “four for four” and I
talk about wanting you to take a medicine, to stay physically active, to
supplement low levels of vitamin D, and to not smoke- this is why. I hope that you
found the review of this article valuable and I would love to hear your
own personal comments, questions and thoughts, down in the section below and
if you want to hear more content like this video please take a moment and
subscribe, to the channel. You can do that by clicking that little red button. Until
my next video, take care

21 thoughts on “MS Research 2018: Smoking While On Tysabri”

  1. I’m unsurprised, smoking is bad for everything. But how about vaping? I vape, it enabled me to stop smoking completely but I’m still addicted to nicotine although I have decreased the strength significantly (to 3mg).
    Another great video!! 👍

  2. Wow! This is startling! I have a friend who also has MS and recognized the symptoms in me. She helped me get diagnosed. She had to quit smoking and it was so hard on her. I will have to show her this video and the great choice she made. She vapes THC though for the pain. Is that just as bad for us? She is trying to get me to stop my pain meds (tramadol) and start vaping also; but I did watch the video you posted on THC and how it effects our cognitive skills. We have so much to contend with. Also, I would just like to say I love this format. It is straight to the point, but yet is packed with great information. Thanks you, for considering what we your viewers like! Have a great Sunday!

  3. Wow, I'm so glad I never smoked. I know how hard it is to quit , albeit anecdotally by watching the difficulty people whom I love in my life have, trying to quit. I'm loving these research paper videos. It's a great addition for MSer's like me, to add to our education. Keep them coming! Thank you for your time and dedication to this disease and sharing your knowledge and experience!

  4. Thank you for making all this this info so much more accessible and reminding us all how important our whole body health is. My fatigue has made me want to go back to smoking, I quit 2 years ago and had my first attack 14 months ago.

  5. Can we do a smoking mj and cbd helpful/ hindering. Plus I really loved the MRI magnet video, and the touch of temputure. The cognitive vid too was great. I need and love this channel cause there is a lack of material info that soley applys to me a ms savage. But found this ♥ I enjoy you and understand you which are BIG compliments coming from me. I had the biggest attack this year-summer couldn't walk, talk or see properly. Slowly getting back to old me but I'm positive it's gonna happen. 2019 alot of life changes which I think will better me and the lifestyle of my family members. My oldest daughter I see signs of ms but she also has TTP so my ms has always taken a back seat. She's been in a 2 yr remission, so … Blessed. I would like to see more on climate temps – I have been taking large amounts of Baclofen on cold snow days the spasms are errrrrrrrrr. Plus everyone thinks my summer big attack was due to the heatwave. I love the mix of scientific and general ( might apply to you ) the everyday life stuff …. Just thank you!!!

  6. In the process of quitting after being diagnosed a few months ago. I am using vaping to do so. I am not on a dmt yet but have just gotten govt funding approval for tecfidera and am waiting to start
    If this kind of disease activity can happen on an effective drug I hate to imagine what it must do to those not on a dmt currently like myself.
    Thanks for the video I will watch it whenever I feel like a cigarette 👍

  7. Being respectful for your time, at first couple of questions (i'm native Russian speaker, so just for being sure that i translated context correctly):
    You mean in this video that even if with Tysabri smoking cause 1/3 times higher risk of increasing disease activity, than we can assume about how risky (means, even higher risks) could be smoking during taking other medications? Or it's just about Tysabri and we should avoid any speculations and just use common sense in health caring ("smoking kill")?
    And i've never heard before anything about vitamin D during MS. I see you are already talking about that in some of your previous videos and i will found it later while watching them, but until then i don't really understand meaning of "supplement low". Does it mean that we should hold it at low level or actually we should avoid low level of vitamin D? 🙂

    And if you have one more minute, just for reading gratitude:
    Found your channel from Reddit and thank you for all of your effort for making the videos! it's really cool to see such involved and open for discussions doctor, especially when your own doctor(s) behave pretty much formally. It could be really important for someone for do not feeling themselves as just one more "unit in MS statistics"!

  8. Dr Boster, do you have any idea if nicotine chewing gum has any effect on MS?
    I gave up (quite heavy smoking), one of the better choices ever
    Thanks for the vid 👍
    3 for 4 here

  9. THAT is not rocket science! I used to smoke. Stopped cold years ago when I did the math. However, my mom and sister could not in spite of ill health, wouldn't even try. Just don't get it. It is obviously a hard addiction for some and not for others. Not unlike any addiction?
    Good can of worms, Doc! Lo the nurse in Fl
    Take a look at my pic here. ..we've all had a patient like that…lol

  10. Interesting. Has anyone spent time researching whether MS immune systems might actually be working perfectly and hunting something that's trapped/stored in the myelin that shouldn't be there, perhaps that's heightened with the chemicals taken in by smoking? Just a thought. Let's get this figured out! Thanks for all your work Dr. B!

  11. I don’t smoke, so this is a nonissue for me. But I do enjoy reading the research you post on Twitter and listening to your thoughts on research you find valuable. It’s been a welcome addition to your YouTube channel!

  12. It continues to surprise me how bad smoking is for us in almost all aspects. 38% increased risk of an MS attack is not a risk I’d take. Thank goodness I never smoked.
    Thanks Dr. Boster for this video.

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